Abstract
Aminolysis of 2(5H)-furanone leads to 3-alkylamino-4-hydroxy-N-alkylbutyramides which easily form hydroxy derivatives of thiourea. The latter, depending on the protonation or quaternization site, easily undergo cyclization to thiazolidine and oxazolidine derivatives.
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Translated from Khimiya Geterotsiklicheskilch Soedinenii No. 12, pp. 1629–1632, December, 1985.
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Tyukhteneva, Z.I., Badovskaya, L.A., Kozlovskaya, I.N. et al. Synthesis of 2-(2-arylamino-3-alkyloxazolidynyl-4)- and 2-(2-arylamino-3-alkylthiazolidynyl-4-N-alkylacetamides from 2(5H)-furanone. Chem Heterocycl Compd 21, 1339–1342 (1985). https://doi.org/10.1007/BF00842956
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DOI: https://doi.org/10.1007/BF00842956