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Studies on advanced glycation end products by recent mass spectrometric techniques

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Summary

The results obtained by different mass spectrometric approaches in the field of advanced glycation of proteins are reported and discussed in detail in comparison with those obtained by other analytical methodologies (fluorescence and absorbance spectroscopies, radioimmunoassay, enzyme-linked immunosorbent assay). They have been subdivided in three main groups: analysis on degraded glycated proteins, direct analysis of glycated proteins and studies on the reaction between protected lysine and glucose. The general overview so achieved indicate mass spectrometry as a particularly valid analytical method in this field of research.

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Article 23 June 2022

Ieva Bagdonaite, Stacy A. Malaker, … Nichollas E. Scott

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Authors and Affiliations

  1. Istituto di Medicina Interna - Patologia Medica, via Giustiniani, 2, I-35100, Padova, Italy

    A. Lapolla & D. Fedele

  2. CNR Area di Ricerca, Padova, Italy

    P. Traldi

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  1. A. Lapolla
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  2. D. Fedele
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  3. P. Traldi
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Lapolla, A., Fedele, D. & Traldi, P. Studies on advanced glycation end products by recent mass spectrometric techniques. Amino Acids 6, 65–96 (1994). https://doi.org/10.1007/BF00808124

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  • DOI: https://doi.org/10.1007/BF00808124

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