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Plasma free amino acid profiles and nutrition proteins in chronic renal failure; effect of dialysis treatment

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Summary

A well preserved nutritional status is beneficial in chronically uremic patients for slowing the pace of deterioration of renal function, and delaying the need for dialysis therapy. The purpose of this study was to assess the nutritional profile of 10 patients in a steady state of advanced CRF, and of 15 patients with terminal renal failure immediately prior to their first hemodialysis session (J0), and 7, 14, 45, 60, days post start of dialysis. Patients were 18 to 65 years old with total plasma proteins ≥ 60g/1. Plasma concentrations of amino acids, nutrition proteins, apolipoproteins A1, and B were evaluated. Non inflammatory reaction was evaluated by determination of alpha-1-acid glycoprotein, and C reactive protein. The data (mean ± 1 SD) were compared with mean values of 15 healthy individuals.

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Authors and Affiliations

  1. Laboratoire de Biochimie, Hôpital de la Salpêtrière, 47 Bd de l'hôpital, F-75651, Paris Cedex 13, France

    S. Troupel

  2. Laboratoire de Biochimie, Hôpital Bichat, 47 Bd de l'hôpital, F-75651, Paris Cedex 13, France

    G. Le Moel, A. Bouten, V. Lecon & J. Agneray

  3. Service de Néphrologie, Hôpital Bichat, 47 Bd de l'hôpital, F-75651, Paris Cedex 13, France

    H. Fessi, G. Stamatakis & JP. Mery

  4. Service de Néphrologie, Hôpital de la Salpêtrière, 47 Bd de l'hôpital, F-75651, Paris Cedex 13, France

    Z. Boukhalfa & C. Jacobs

Authors
  1. S. Troupel
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  2. G. Le Moel
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  3. A. Bouten
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  4. H. Fessi
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  5. Z. Boukhalfa
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  6. G. Stamatakis
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  7. V. Lecon
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  8. JP. Mery
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  9. J. Agneray
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  10. C. Jacobs
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Troupel, S., Le Moel, G., Bouten, A. et al. Plasma free amino acid profiles and nutrition proteins in chronic renal failure; effect of dialysis treatment. Amino Acids 2, 127–132 (1992). https://doi.org/10.1007/BF00806083

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  • DOI: https://doi.org/10.1007/BF00806083

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