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Chemistry of Heterocyclic Compounds

, Volume 15, Issue 5, pp 507–514 | Cite as

Indolizines. 6. Relative reactivities of isomeric 6-, 7-, and 8-ethoxycarbonylindolizine derivatives

  • T. S. Loseva
  • M. S. Goizman
  • G. G. Dvoryantseva
  • E. E. Mikhlina
  • L. N. Yakhontov
Article
  • 27 Downloads

Abstract

The kinetics of the alkaline hydrolysis of 2-phenyl-6-, -7-, and -8-ethoxycarbonylindolizines were studied. The rate constants for the hydrolysis of these compounds and the indexes of the dissociation constants of 2-phenylindolizine-6-,-7-, and -8-carboxylic acids were determined by spectrophotometry. The indexes of the electronic structures and reactivities of 2-methyl-6-, -7-, and -8-ethoxycarbonylindolizines were calculated from theory.

Keywords

Hydrolysis Organic Chemistry Carboxylic Acid Spectrophotometry Dissociation Constant 
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Literature cited

  1. 1.
    T. S. Loseva, M. S. Goizman, L. M. Alekseeva, O. R. Shvarts, E. E. Mikhlina, and L. N. Yakhontov, Khim. Geterotsikl. Soedin., No. 6, 802 (1978).Google Scholar
  2. 2.
    E. E. Mikhlina, A. D. Yanina, T. S. Loseva, K. F. Turchin, and L. N. Yakhontov, Khim. Geterotsikl. Soedin., No. 7, 977 (1974).Google Scholar
  3. 3.
    T. S. Loseva, A. D. Yanina, E. E. Mikhlina, and L. N. Yakhontov, Khim. Geterotsikl. Soedin., No. 2, 209 (1976).Google Scholar
  4. 4.
    T. S. Loseva, A. D. Yanina, E. E. Mikhlina, and L. N. Yakhontov, Khim. Geterotsikl. Soedin., No. 3, 348 (1976).Google Scholar
  5. 5.
    L. M. Alekseeva, G. G. Dvoryantseva, M. S. Goizman, T. S. Loseva, A. D. Yanina, E. E. Mikhlina, Yu. N. Sheinker, and L. N. Yakhontov, Khim. Geterotsikl. Soedin., No. 11, 1540 (1976).Google Scholar
  6. 6.
    K. Doerfel, Statistics in Analytical Chemistry [Russian translation], Mir, Moscow (1969).Google Scholar
  7. 7.
    A. Albert and E. Serjeant, Ionization Constants of Acids and Bases, Methuen (1962).Google Scholar

Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • T. S. Loseva
    • 1
  • M. S. Goizman
    • 1
  • G. G. Dvoryantseva
    • 1
  • E. E. Mikhlina
    • 1
  • L. N. Yakhontov
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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