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Synthesis of naphthyridines

I. New method for the preparation of 2,3-dihydrobenzo[h][1,6]naphthyridin-4-(1H)-ones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A new method for the synthesis of 2,3-dihydrobenzo[h][1,6]naphthyridin-4-(1H)-ones, which consists in cyclization of 4-(β-carboxyethylamino)quinoline-3-carboxylic acids by heating them in acetic anhydride in the presence of potassium acetate, is proposed.

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Literature cited

  1. A. F. Bekhli, Dokl. Akad. Nauk SSSR,101, 679 (1955).

    Google Scholar 

  2. A. F. Bekhli and F. S. Mikhailitsyn, Abstracts of Papers Presented at the Third International Congress on Heterocyclic Chemistry, Sendai, Japan (1971), p. 317.

  3. F. S. Mikhailitsyn, A. F. Bekhli, and S. A. Rabinovich, Khim.-Farmats. Zh., No. 12, 19 (1974).

    Google Scholar 

  4. G. C. Wright, E. I. Watson, F. F. Ebetino. G. Lougheed, B. F. Stevenson, A. Winterstein, R. K. Bickerton, R. P. Halliday, and D. T. Pals, J. Med. Chem.,14, 1060 (1971).

    Google Scholar 

  5. B. Riegel, G. R. Lappin, B. H. Adelson, R. I. Jackson, C. J. Albisetti, R. M. Dodson, and R. H. Baker, J. Amer. Chem. Soc.,68, 1264 (1946).

    Google Scholar 

  6. A. R. Surry (Sterling Drug, Inc.), US Patent No. 3362954; Chem. Abstr.,69, P 10382q (1968).

    Google Scholar 

  7. E. F. Elslager and F. H. Tendick, J. Med. Pharm. Chem.,5, 546 (1962).

    Google Scholar 

  8. D. Kaminsky (Warner-Lambert Pharmaceutical Co.), French Patent No. 2002888; Chem. Abstr.,72, P 90322v (1970).

    Google Scholar 

  9. L. Fieser and M. Fieser, Reagents for Organic Synthesis, Vol. 1, Wiley-Interscience.

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Authors and Affiliations

  1. E. I. Martsinovskii Institute of Medicinal Parasitology and Tropical Medicine, Moscow

    F. S. Mikhailitsyn, E. M. Braude & A. F. Bekhli

Authors
  1. F. S. Mikhailitsyn
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  2. E. M. Braude
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  3. A. F. Bekhli
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1660–1662, December, 1975.

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Mikhailitsyn, F.S., Braude, E.M. & Bekhli, A.F. Synthesis of naphthyridines. Chem Heterocycl Compd 11, 1405–1407 (1975). https://doi.org/10.1007/BF00764536

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  • DOI: https://doi.org/10.1007/BF00764536

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