Abstract
3,3-Disubstituted 2-iminoindolines and the corresponding 10,10-disubstituted tetrahydropyrimido-[1,2-a] indoles, including compounds with spiran structures, were synthesized by reaction of 1-phenyl-2-acylhydrazines and l-phenyl-2-acylpyrazolidines geminally substituted at theα-carbon atom of the acyl residue with phosphorus oxychloride. An instance of cleavage of the methyl group was detected.
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Yu. N. Portnov. G. A. Golubeva, and A. N. Kost, Khim. Geterotsikl. Soedin., 61 (1972).
J. Kebrle and K. Hoffmann. Helv. Chim. Acta,36, 116 (1956).
M. Nakagawa and T. Hino, Tetrahedron,26, 4491 (1970).
R. J. Sundberg, Chemistry of Indoles, Academic Press, New York-London (1970), p. 316.
G. A. Golubeva, Yu. N. Portnov, A. N. Kost, and L. A. Sviridova, Khim. Geterotsikl. Soedin., 118 (1971).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1632–1635, December, 1975.
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Kost, A.N., Golubeva, G.A., Zabrodnyaya, V.G. et al. Synthesis of 3,3-disubstituted 2-iminoindolines by cyclization of 1-phenyl-2-acylhydrazines. Chem Heterocycl Compd 11, 1383–1386 (1975). https://doi.org/10.1007/BF00764531
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DOI: https://doi.org/10.1007/BF00764531