, Volume 14, Issue 2, pp 119–122 | Cite as

Suppressive effect of spinach extract on the formation of melanin in B16 mouse melanoma cells

  • Masuko Kobori
  • Yasuto Sasaki
  • Kazuki Shinohara
Technical Report


A non-dialyzable extract of fresh spinach leaves exhibited a strong antioxidant activity towards oxidation of linoleic acid and suppressed the melanin formation of a mouse melanoma cell line, B16 melanoma 4A5, without any significant effect on the proliferation of cells.

Key words

B16 melanoma formation of melanin spinach extract 


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Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Masuko Kobori
    • 1
  • Yasuto Sasaki
    • 2
  • Kazuki Shinohara
    • 1
  1. 1.National Food Research InstituteTsukuba, IbarakiJapan
  2. 2.Nitto Flour Milling Co., Ltd.TokyoJapan

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