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Modeling of cell culture processes

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Abstract

Models of cell processes can be particularly useful in simulating, optimizing and controlling cell culture systems. Models reported in the literature are of various degrees of biological structure and mathematical complexity and describe cell growth, death, metabolism, and product formation, alone or in combination with each other. This paper reviews these modeling efforts, discusses their results, potential and limitations, and identifies areas where future modeling studies may be especially valuable.

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  1. School of Chemical Engineering, Georgia Institute of Technology, 30332-0100, Atlanta, GA, USA

    Evangelos Tziampazis & Athanassios Sambanis

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  1. Evangelos Tziampazis
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Tziampazis, E., Sambanis, A. Modeling of cell culture processes. Cytotechnology 14, 191–204 (1994). https://doi.org/10.1007/BF00749616

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