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Synthesis of alkylamine derivatives of 1-aryl-5-hydroxyindole

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Condensing substituted l-aryl-5-hydroxyindoles with bisdimethylaminomethane, or sodium-alcohol reduction of l-aryl-2-methyl-3-acetyl-5-methoxyindoles gives 4-dimethylaminomethyl and 3-alkylamino derivatives of 1-aryl-5-hydroxy (methoxy) indole, isolated as the hydrochlorides.

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Grinev, A.N., Shvedov, V.I. & Panisheva, E.K. Synthesis of alkylamine derivatives of 1-aryl-5-hydroxyindole. Chem Heterocycl Compd 2, 287–288 (1967). https://doi.org/10.1007/BF00742369

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  • DOI: https://doi.org/10.1007/BF00742369

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