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Cytotechnology

, Volume 5, Supplement 1, pp 57–58 | Cite as

Cell metabolism measurements in culture via microelectronic biosensors

  • M. Grattarola
  • S. Martinoia
  • G. Carlini
  • A. Cambiaso
  • M. Tedesco
  • M. T. Parodi
  • G. Ferri
Selected Paper

Abstract

Silicon-based H+-sensitive biosensors in proximity to a cell population detect variations in cell metabolism via local measurements of changes in pH. The feasibility of this approach is shown in the case of ISFET devices.

Keywords

Cell Population Cell Metabolism Local Measurement Metabolism Measurement Sensitive Biosensor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. [1]
    Sibbald A. (1986) “Recent advances in field-effect chemical microsensors”, J. Molecular Electronics, 2, 51–83.Google Scholar
  2. [2]
    Parce J. W. et al. (1989) “Detection of cell-affecting agents with a silicon biosensor”, Science, 246, 243–247.Google Scholar

Copyright information

© Kluwer Academic Publishers 1991

Authors and Affiliations

  • M. Grattarola
    • 1
  • S. Martinoia
    • 1
  • G. Carlini
    • 1
  • A. Cambiaso
    • 1
  • M. Tedesco
    • 1
  • M. T. Parodi
    • 1
  • G. Ferri
    • 1
  1. 1.Biophysical and Electronic Engineering DepartmentUniversity of GenovaGenovaItaly

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