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Conversion of 2-acetamido-1-thiochromone to the corresponding 4-chloro and 4-amino derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-Acetimido-4-chloro-2H-1-thiochromene, in which the chlorine atom is exchanged by hydroxy and amino groups, was synthesized by the action of phosphorus oxychloride on 2-acetamido-1-thiochromone. It was established on the basis of the IR, UV, PMR, and mass spectra that the product of the reaction of this compound with aniline has the 2-acetaraido-1-thiochromene structure.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 622–625, May, 1978.

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Glozman, O.M., Zhmurenko, L.A. & Zagorevskii, V.A. Conversion of 2-acetamido-1-thiochromone to the corresponding 4-chloro and 4-amino derivatives. Chem Heterocycl Compd 14, 507–511 (1978). https://doi.org/10.1007/BF00673333

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  • DOI: https://doi.org/10.1007/BF00673333

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