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Researches on furans

XLIV. Reaction of 2-α-chloropro py if ur an with sodium cyanide

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is found that, unlike 2-chloromethylfuran, 2-(α-chloropropyl)furan reacts with sodium cyanide in dimethylformamide to give a mixture of isomeric nitriles consisting ofα-(2-furyl)-butyronitrile and 5-propylpyromuconitrile. The structures of the acids obtained by hydrolysis of these nitriles, are confirmed by retrosynthesis.

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References

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For Part XLII see [2].

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Novitskii, K.Y., Gresl, K. & Yur'ev, Y.K. Researches on furans. Chem Heterocycl Compd 2, 633–634 (1968). https://doi.org/10.1007/BF00664820

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  • DOI: https://doi.org/10.1007/BF00664820

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