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Synthesis and reactions of 9-hydroxy-(α-alkoxycarbonylalkyl)-4-azafluorenes

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The Reformatsky reaction with 4-azafluorenone has given 9-hydroxy-9-(α-alkoxycarbonylalkyl)-4-azafluorenes. The course of this reaction with respect to the α-haloester used, and the conversion of these hydroxyesters into hydroxy- and α,Β-unsaturated acids have been examined.

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Literature Cited

  1. N. S. Prostakov, V. P. Shalimov, E. V. Kurglyak, A. I. Levov, A. V. Varlamov, and T. A. Ventslavskaya, “Synthesis and examination of physiologically active compounds,” in: Abstracts of Papers, Republican Scientific Conference, Vilnius (1988), p. 102.

  2. N. S. Prostakov, A. V. Varlamov, B. N. Anisimov, N. M. Mikhailova, G. A. Vasil'ev, P. I. Zakharov, and M. A. Galiullin,Khim. Geterotsikl. Soedin., No. 9, 1234 (1978).

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 81–85, January, 1991.

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Prostakov, N.S., Kruglyak, E.V., Shalimov, V.P. et al. Synthesis and reactions of 9-hydroxy-(α-alkoxycarbonylalkyl)-4-azafluorenes. Chem Heterocycl Compd 27, 67–70 (1991). https://doi.org/10.1007/BF00633221

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  • DOI: https://doi.org/10.1007/BF00633221

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