Chemistry of Heterocyclic Compounds

, Volume 27, Issue 1, pp 27–30 | Cite as

Tetrafluoroboric acid — A new catalyst for the synthesis of 1,3-dioxolanes. Preparation of hydroxyacetone

  • A. A. Gevorkyan
  • P. I. Kazaryan
  • O. V. Avakyan
  • R. A. Vardanyan


It is established that tetrafluoroboric acid (HBF4) is an effective catalyst for halogen substitution reactions of oxiranes (epichlorohydrin and 1-bromo-3-methyl-2,3-epoxybutane) with aldehydes and ketones, forming 1,3-dioxolanes in high yields.


Organic Chemistry Aldehyde Ketone Halogen Substitution Reaction 
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Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • A. A. Gevorkyan
    • 1
  • P. I. Kazaryan
    • 1
  • O. V. Avakyan
    • 1
  • R. A. Vardanyan
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Armenian SSRErevan

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