Chemistry of Natural Compounds

, Volume 18, Issue 3, pp 255–259 | Cite as

Synthesis of methyl derivatives of uronic acids. I. Synthesis of methyl (methylα-D-galactopyranosid)uronate and its 2-, 3-, and 4-O-methyl ethers

  • V. I. Grishkovets
  • A. E. Zemlyakov
  • V. Ya. Chirva
Article
  • 41 Downloads

Abstract

Alternative unidirectional methods for synthesizing methyl (methyl α-D-galactopyranosid)uronate and its mono-O-methyl ethers by the oxidation (with CrO3-H2SO4-acetone) of the corresponding methyl O-benzyl-O-methyl-α-D-galactopyranosides having unsubstituted 6-OH groups to the corresponding methyl O-benzyl-O-methyl-α-D-galactouronic acids followed by esterification with CH2N2 and the catalytic hydrogenolysis of the benzyl groups are proposed.

Keywords

Anhydrous Sodium Sulfate Uronic Acid Diazomethane Methyl Ether Galacturonic Acid 

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • V. I. Grishkovets
  • A. E. Zemlyakov
  • V. Ya. Chirva

There are no affiliations available

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