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Chemistry of Natural Compounds

, Volume 21, Issue 4, pp 455–460 | Cite as

Pentaketide metabolites of mutants and the biosynthesis of melanin inVerticillium tricorpus

  • N. N. Stepanichenko
  • L. N. Ten
  • A. A. Tyshchenko
  • V. M. Shevtsova
  • S. Z. Mukhamedzhanov
  • A. G. Kas'yanenko
Article
  • 46 Downloads

Abstract

From mutants of the fungusVerticillium tricorpus Isaac., having various genetic blocks in the biosynthesis of melanin, we have isolated and identified scytalone, flaviolin, 3,3′-biflavinolin, 2-hydroxyjuglone, vermelone, and 1,8-dihydroxynaphthalene, which, in combination with the results of complementation analysis, has enabled the main stages of the biosynthesis of melanin inV. tricorpus to be established. The results on the inhibition of the biosynthesis of melanin by tricyclazole in natural isolates ofV. tricorpus indicates that the initital stages of the biosynthesis of melanin inV. tricorpus up to the formation of 1,3,8-trihydroxynaphthalene are identical with those ofVerticillium dahliae.

Keywords

Acetone Extract Naphthoquinone Natural Isolate Tricyclazole Mild Acid Hydrolysis 

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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • N. N. Stepanichenko
  • L. N. Ten
  • A. A. Tyshchenko
  • V. M. Shevtsova
  • S. Z. Mukhamedzhanov
  • A. G. Kas'yanenko

There are no affiliations available

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