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Chemistry of Natural Compounds

, Volume 21, Issue 5, pp 657–660 | Cite as

Acylation of steroid alcohols with 3-carboxypropanamido acids

  • L. N. Volovel'skii
  • I. A. Rastrepina
  • N. V. Popova
  • V. N. Koryukina
  • S. P. Kustova
Article
  • 39 Downloads

Abstract

Using N-(3-carboxypropanoyl)-β-phenyl-α-alanine as a model it has been established that when steroid alcohols are esterified with 3-carboxypropanamido acids, the carboxy group of the succinic acid residue takes part in the esterification reaction. In order to obtain a steroid ester of a 3-carboxypropanamido acid in which the carboxyl of the amino acid is the esterifying group, the carboxy group of the succinic acid residue must first be esterified.

Keywords

Alanine Acid Chloride Carboxy Group Thionyl Chloride Dihydrotestosterone 

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Literature cited

  1. 1.
    J. Cason, Org. Synth., Coll. Vol. III, 169–171 (1955).Google Scholar

Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • L. N. Volovel'skii
  • I. A. Rastrepina
  • N. V. Popova
  • V. N. Koryukina
  • S. P. Kustova

There are no affiliations available

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