Chemistry of Natural Compounds

, Volume 21, Issue 5, pp 553–566 | Cite as

Chemical modification of the arginine residues of proteins and peptides

  • V. M. Makhnyr


Methods for the chemical modification of arginine residues with the aid of butan-2,3-dione and its oligomers, cyclohexane-1,2-dione, phenylglyoxal, tetraethoxy-propane, nitromalondialdehyde, and pentane-2,4-dione are considered. The conditions for performing the reactions and their mechanism are given and the stability of the products formed and methods for their identification are discussed.


Arginine Borate Dione Ornithine Acetylacetone 


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Copyright information

© Plenum Publishing Corporation 1986

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  • V. M. Makhnyr

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