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Chemistry of Natural Compounds

, Volume 18, Issue 2, pp 215–219 | Cite as

Analogs of D(+)-pantothenic acid. VI. Synthesis of D-, L-, and DL-4′-amino-4′-deoxypantothenic acid

  • V. M. Kopelevich
  • L. N. Bulanova
  • V. I. Gunar
Article

Abstract

A new analog of pantothenic acid, DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid, has been synthesized and it has been separated into stereoisomer. D-, L-, and DL-N-(4-Amino-2-hydroxy-3,3-dimethylbutyryl)-β-alanines — amino analogs of pantothenic acid — have been synthesized by the condensation of the N-hydroxysuccinimide esters of N-BOC-D-, -L-, and -DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acids with β-alanine, followed by the elimination of the protective groups.

Keywords

Lactam Pantothenic Acid Phthalimide Sodium Tetrahydroborate Ethano 

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • V. M. Kopelevich
  • L. N. Bulanova
  • V. I. Gunar

There are no affiliations available

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