Abstract
A new analog of pantothenic acid, DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid, has been synthesized and it has been separated into stereoisomer. D-, L-, and DL-N-(4-Amino-2-hydroxy-3,3-dimethylbutyryl)-β-alanines — amino analogs of pantothenic acid — have been synthesized by the condensation of the N-hydroxysuccinimide esters of N-BOC-D-, -L-, and -DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acids with β-alanine, followed by the elimination of the protective groups.
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Additional information
“Vitaminy” Scientific-Production Amalgamation, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 235–239, March–April, 1982.
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Kopelevich, V.M., Bulanova, L.N. & Gunar, V.I. Analogs of D(+)-pantothenic acid. VI. Synthesis of D-, L-, and DL-4′-amino-4′-deoxypantothenic acid. Chem Nat Compd 18, 215–219 (1982). https://doi.org/10.1007/BF00577198
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DOI: https://doi.org/10.1007/BF00577198