Abstract
The acylation of 2,3-benzo-18-crown-6 with carboxylic acids in the presence of polyphosphoric acid has given new acyl derivatives which have been reduced to the corresponding alkyl derivatives. The ionophoric activities of the compounds have been investigated on mitochondrial membranes.
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B. A. Tashmukhamedov, A. I. Gagel'gans (Gagelgans), A. V. Shkinev, U. Z. Mirkhodjaev, M. V. Zamaraeva, and A. K. Tashmukhamedova, in: Frontiers in Bioorganic Chemistry and Molecular Biology; An Interantional Symposium, Moscow and Tashkent (1978), p. 439.
B. A. Tashmukhamedov, et al., Bioorg. Khim.,5, 429 (1979).
A. V. Shkinev, A. I. Gagel'gans, and A. K. Tashmukhamedova, Khim. Prir. Soedin., 243 (1979).
A. V. Shkinev, A. I. Gagel'gans, A. K. Tashmukhamedova, and B. A. Tashmukhamedov, Khim. Prir. Soedin., 242 (1979).
W. W. Parish, R. E. Scott, and C. W. McCausland, J. Org. Chem.,43. No. 24, 4577 (1978).
A. K. Tashmukhamedova, et al., Biorg. Khim.,4, 806, 1232 (1978);6, 281, 1099 (1980).
A. V. Shkinev, A. I. Gagel'gans, L. Ya. Yukel'son, and B. A. Tashmukhamedov, Byull. Éksp. Biol. Med.,85, No. 4, 422 (1978).
British Patent, No. 1,108,921 (1964).
C. J. Pedersen, J. Am. Chem. Soc.,89, 7017 (1967).
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Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 634–637, September–October, 1983.
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Shkinev, A.V., Asrarov, M.I., Gagel'gans, A.I. et al. Synthesis and membrane activity of new derivatives of 2,3-benzo-18-crown-6. Chem Nat Compd 19, 597–600 (1983). https://doi.org/10.1007/BF00576093
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DOI: https://doi.org/10.1007/BF00576093