Chemistry of Natural Compounds

, Volume 19, Issue 5, pp 580–582 | Cite as

Synthesis of derivatives of pentopyranic acid

  • L. N. Kulinkovich
  • V. A. Timoshchuk


N4-Benzoylcytosine 1-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) has been obtained with a yield of 70% by the glycosylation of the trimethylsilyl derivative of N4-benzoylcytosine with methyl 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronate in the presence of three equivalents of SnCl4 as condensing agent. Cytosine 1-(β-D-glucopyranosiduronamide) (IV) — the amide of pentopyranic acid — has been synthesized in practically quantitative yield by the ammonolysis of the nucleoside (I).


Nucleoside Aspergillus Oryzae Benzoyl Chloride Trimethylsilyl Derivative Disk Electrophoresis 


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Literature cited

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • L. N. Kulinkovich
  • V. A. Timoshchuk

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