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Synthesis of new antiatheromatous drugs. Study of the esterification of 17β-hydroxy-5α-androstan-3-one

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Abstract

The acylation of dihydrotestosterone with propionyl and p-chlorophenoxyisobutyryl chlorides leads to the formation of dihydrotestosterone esters and the 3-enol acylates of the dihydrotestosterone esters. The acid hydrolysis of the 3-enol acylates converts them into the corresponding dihydrotestosterone esters.

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Authors
  1. L. N. Volovel'skii
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  2. V. N. Koryukina
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  3. N. V. Popova
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  4. I. A. Rastrepina
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  5. L. K. Borozenets
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Additional information

Khar'kov Scientific-Research Institute of Endocrinology and Hormone Chemistry. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 473–476, July–August, 1983.

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Volovel'skii, L.N., Koryukina, V.N., Popova, N.V. et al. Synthesis of new antiatheromatous drugs. Study of the esterification of 17β-hydroxy-5α-androstan-3-one. Chem Nat Compd 19, 444–446 (1983). https://doi.org/10.1007/BF00575703

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  • DOI: https://doi.org/10.1007/BF00575703

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