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Chemistry of Natural Compounds

, Volume 19, Issue 6, pp 704–709 | Cite as

Steroid compounds of marine sponges. I. Sterols ofEsperiopsis digitata

  • L. K. Shubina
  • T. N. Makar'eva
  • V. M. Boguslavskii
  • V. A. Stonik
Article
  • 54 Downloads

Abstract

From extracts of the Far Eastern spongeEsperiopsis digitata, by column chromatography on silica gel we have isolated three fractions of steroid compounds. The fractions isolated have been analyzed with the aid of TLC, GLC-MS, PMR, and13C NMR. The least polar fraction (1) had a Rf value identical with that of cholesterol and represents the total free steroids. After argentation column chromatography, 13 components were identified in it, the main one being cholesterol. The more polar fraction (2) consisted of a combination of 3β-hydroxychol-5-en-24-al and 3β-hydroxy-24-norchol-5-en-23-al. The most polar of the fractions isolated — fraction (3) — consisted of a single component which was identified as cholesta-5,25-diene-3β,24ξ-diol.

Keywords

Diol Polar Fraction Desmosterol Steroid Compound Fucosterol 

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Literature cited

  1. 1.
    I. Rubinstein, L. J. Goad, A. D. H. Clague, and L. J. Mulheirn, Phytochemistry,15, 195 (1976).CrossRefGoogle Scholar
  2. 2.
    L. Bohlin, U. Sjöstrand, C. Djerassi, and B. W. Sullivan, J. Chem. Soc. Perkin Trans. I, 1023 (1981).CrossRefGoogle Scholar
  3. 3.
    P. Eneroth, K. Hellstrom, and R. Ryhage, J. Lipid Res.,5, 245 (1964).PubMedGoogle Scholar
  4. 4.
    Y. M. Sheikh and C. Djerassi, Tetrahedron,30, 4095 (1974).CrossRefGoogle Scholar
  5. 5.
    B. A. Knights, J. Gas Chromatogr.,5, 273 (1967).CrossRefGoogle Scholar
  6. 6.
    A. Kanazawa, S. I. Teshima, and T. Ando, Comp. Biochem. Physiol.,57B, 517 (1977).Google Scholar
  7. 7.
    M. V. Piretti and G. P. Serrazanetti, Comp. Biochem. Physiol.,66B, 301 (1980).Google Scholar
  8. 8.
    M. Kobayashi, M. Hishizawa, K. Todo, and H. Mitsuhashi, Chem. Pharm. Bull.,21, 323 (1973).CrossRefGoogle Scholar
  9. 9.
    J. W. ApSimon and D. J. Burnell, Comp. Biochem. Physiol.,65B, 567 (1980).Google Scholar
  10. 10.
    J. W. Blunt and J. B. Stothers, Org. Magn. Reson.,9, 439 (1977).CrossRefGoogle Scholar
  11. 11.
    M. Morisaki, S. Kidooka, and N. Ikekawa, Chem. Pharm. Bull.,24, 3214 (1976).CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • L. K. Shubina
  • T. N. Makar'eva
  • V. M. Boguslavskii
  • V. A. Stonik

There are no affiliations available

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