Chemistry of Natural Compounds

, Volume 20, Issue 4, pp 424–426 | Cite as

Glycosides of marine invertebrates. XXVI. Holothurin A from the Pacific Ocean holothurianHolothvria squamifera. Isolation of the native aglycone

  • N. S. Ivanova
  • O. F. Smetanina
  • T. A. Kuznetsova
Article
  • 39 Downloads

Abstract

The known triterpene tetraoside holothurin A has been isolated from the Pacific Ocean holothurianHolothuria squamifera. By using two independent methods — enzymatic cleavage and two-stage Smith degradation — 22,25-epoxyholost-9(11)-ene-3β,12α,17α-triol, C30H46O6, which is the native aglycone of holothurin A, was obtained. The structure of the native aglycone has been established on the basis of the results of IR, mass, and PMR spectroscopy.

Keywords

Glycoside Pacific Ocean Marine Invertebrate Enzymatic Cleavage Tetrao 

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Literature cited

  1. 1.
    G. K. Oleinikova, T. A. Kuznetsova, N. S. Ivanova, A. I. Kalinovskii, N. V. Rovnykh, and G. B. Elyakov, Khim. Prir. Soedin., 464 (1982).Google Scholar
  2. 2.
    I. Kitagawa, T. Nishino, T. Matsuno, H. Akutsu, and Y. Kyogoku, Tetrahedron Lett., 985 (1978).Google Scholar
  3. 3.
    I. Kitagawa, T. Nishino, and Y. Kyogoku, Tetrahedron Lett., 1419 (1979).Google Scholar
  4. 4.
    J. D. Chanley and C. Rossi, Tetrahedron,25, 1897 (1969).CrossRefGoogle Scholar
  5. 5.
    J. D. Chanley and C. Rossi, Tetrahedron,25, 1911 (1969).CrossRefGoogle Scholar
  6. 6.
    G. Habermehl, G. Volkwein, Ann. Chem.,731, 53 (1970).CrossRefGoogle Scholar
  7. 7.
    V. A. Stonik, I. I. Mal'tsev, A. I. Kalinovskii, K. Kondé, and G. B. Elyakov, Khim. Prir. Soedin., 200 (1982).Google Scholar
  8. 8.
    N. I. Shirokova, N. I. Uvarova, and L. A. Elyakova, Khim. Prir. Soedin., 222 (1974).Google Scholar
  9. 9.
    L. I. Strigina, N. S. Chetyrina, and V. V. Isakov, Khim. Prir. Soedin., 169 (1976).Google Scholar

Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • N. S. Ivanova
  • O. F. Smetanina
  • T. A. Kuznetsova

There are no affiliations available

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