Chemistry of Natural Compounds

, Volume 11, Issue 3, pp 392–394 | Cite as

Stereochemical features of diterpene alkaloids in acylation and alkaline hydrolysis reactions

  • M. N. Sultankhodzhaev
  • M. S. Yunusov
  • S. Yu. Yunusov


Relative difficulty of saponifying an acetoxy group at C1 and ease of acylation of a hydroxy group in this position as compared with a hydroxy group C10 has been shown for alkaloids with a lycoctonine skeleton.

The anomalously easy saponification of a C1-acetoxy group in karakolidine acetates is due to the influence of the neighboring C13-hydroxy group.


Hydroxy Group Acetic Anhydride Acylation Reaction Acetoxy Group OCOC 


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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • M. N. Sultankhodzhaev
  • M. S. Yunusov
  • S. Yu. Yunusov

There are no affiliations available

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