Abstract
A new method has been developed for the bromination of thiophene and its derivatives. The method consists in the action of N-bromosuccinimide in acetic anhydride and glacial acetic acid on the thiophene derivatives. In the bromination of 2-acetylthiophene and its derivatives, the bromine replaces the hydrogen atom in the 5 position of the thiophene ring.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 185–187, February, 1973.
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Smirnov, V.A., Lipkin, A.E. Bromination of 2-acetylthiophene and its derivatives. Chem Heterocycl Compd 9, 170–172 (1973). https://doi.org/10.1007/BF00569154
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DOI: https://doi.org/10.1007/BF00569154