Conclusions
1. The amino-acid compositions of two neurotoxins from the venom of the Central Asian cobra have been established. The N-terminal amino-acid residue of toxin (I) is isoleucine and that of toxin (II) leucine. There is the same sequence from the C-end of both toxins — Cys-Asn-Asn-COOH.
2. The role of the individual functional groups (ɛ-amino groups and disulfide bridges) of the amino acids in the lethal action of the toxins has been investigated and discussed.
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Additional information
Institute of Biochemistry, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 62–64, January–February, 1974.
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Turakulov, Y.K., Nishankhodzhaeva, S.A., Sorokin, V.M. et al. Amino-acid composition and terminal amino acids of the toxins of the venom of the central Asian cobra. Chem Nat Compd 10, 55–57 (1974). https://doi.org/10.1007/BF00568222
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DOI: https://doi.org/10.1007/BF00568222