Advertisement

Chemistry of Natural Compounds

, Volume 4, Issue 2, pp 105–108 | Cite as

Analogs of coenzymes of carbohydrate metabolism

IX. Synthesis of N1-methyladenosine diphosphate glucose
  • N. K. Kochetkov
  • E. I. Budovskii
  • V. N. Shibaev
  • S. M. Spiridonova
Article
  • 23 Downloads

Summary

1. The synthesis of N1-methyl-ADGP, an analog of the natural coenzyme adenosine diphosphate glucose, has been synthesized.

2. On the basis of an analysis of the UV spectra and the electrophoretic mobility of derivatives of N1-methyladenosine, the hypothesis has been put forward that at pH 7.5 it exists in solutions in the protonated form.

Keywords

Diphosphate Paper Chromatography DEAE Cellulose Dimethyl Sulfate Paper Electrophoresis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    N.K. Kochetkov, E.I. Budovskii, and V.N. Shibaev, KhPS [Chemistry of Natural Compounds], 1, 409, 1965.Google Scholar
  2. 2.
    N.K. Kochetkov, E.I. Budovskii, and V.N. Shibaev, Biokhim., 28, 741, 1963.Google Scholar
  3. 3.
    E.I. Budowsky and T.N. Drushinina, et al., Biochim. et Biophys. Acta 122, 213, 1966.CrossRefGoogle Scholar
  4. 4.
    N.K. Kochetkov, E.I. Budovskii, V.N. Shibaev, and G.I. Eliseeva, DAN SSSR, 159, 605, 1964.Google Scholar
  5. 5.
    N.K. Kochetkov and E.I. Budowsky, et al., Tetrah., 19, 1207, 1963.CrossRefGoogle Scholar
  6. 6.
    E. Recondo and L. Leloir, Biochem. Biophys. Res. Communs., 6, 85, 1961.CrossRefGoogle Scholar
  7. 7.
    W. J. Kelleher, J. Pharm. Sci. 54, 108, 1965.CrossRefGoogle Scholar
  8. 8.
    T.N. Druzhinina, N.D. Gabrielyan, and M.A. Novikova, Papers at the IVth All-Union Conference on the Chemistry and Metabolism of Carbohydrates [in Russian], Moscow-L'vov, p. 75, 1967.Google Scholar
  9. 9.
    J.W. Jones and R.K. Robins, J. Am. Chem. Soc., 85, 193, 1963.CrossRefGoogle Scholar
  10. 10.
    B.E. Griffin and C.B. Reese, Biochim. et Biophys. Acta, 68, 185, 1963.CrossRefGoogle Scholar
  11. 11.
    J. A. Haines, C.B. Reese, and A. Todd, J. Chem. Soc., 1406, 1964.Google Scholar
  12. 12.
    K.H. Scheit, Biochim. et Biophys. Acta., 119, 425, 1966.CrossRefGoogle Scholar
  13. 13.
    S. Roseman, J. Distler, J. Moffatt, and H. Khorana, J. Am. Chem. Soc., 83, 659, 1961.CrossRefGoogle Scholar
  14. 14.
    N.K. Kochetkov, E.I. Budovskii, and V.N. Shibaev, Izv. Akad. Nauk SSSR, OKhN, 6, 1035, 1962.Google Scholar
  15. 15.
    E.I. Budovskii and V.N. Shibaev, Voprosy med. khimii, 13, 558, 1967.Google Scholar
  16. 16.
    V.M. Peshkova and M. Gromova, Practical Handbook on Spectrophotometry and Colorimetry [in Russian], Moscow, p. 147, 1961.Google Scholar
  17. 17.
    J. T. Park and M.J. Johnson, J. Biol. Chem., 181, 149, 1949.PubMedGoogle Scholar
  18. 18.
    J.G. Moffatt and H.G. Khorana, J. Am. Chem. Soc., 83, 649, 1961.CrossRefGoogle Scholar
  19. 19.
    M.F. Singer, L.A. Heppel, G.W. Rushizky, and H.A. Sober, Biochim. et Biophys. Acta, 61, 474, 1962.Google Scholar

Copyright information

© The Faraday Press, Inc. 1969

Authors and Affiliations

  • N. K. Kochetkov
    • 1
  • E. I. Budovskii
    • 1
  • V. N. Shibaev
    • 1
  • S. M. Spiridonova
    • 1
  1. 1.Institute of the Chemistry of Natural Compounds AS USSRUSSR

Personalised recommendations