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Synthesis of bradykinin

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Chemistry of Natural Compounds Aims and scope

Summary

A new method for the synthesis of bradykinin giving high yields in all stages has been developed. Biological tests of the compounds synthesized have shown that it is identical with the natural hormone.

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References

  1. M. Rocha-e-Silva, W. T. Beraldo, and G. Rosenfeld, Am. J. Physiol., 156, 261, 1949.

    PubMed  Google Scholar 

  2. D. F. Elliott, G. P. Levis, and E. W. Horton, Biochem. J., 74, 16P, 1960.

  3. D. F. Elliott, G. P. Levis, and E. W. Horton, Biochem. Biophys. Res. Commun., 3, 87, 1960.

    Article  CAS  Google Scholar 

  4. R. A. Boissonnas, St. Guttmann, P. A. Jaquenoud, H. Konzett, and E. Sturmer, Experientia, 16, 326, 1960.

    Article  CAS  Google Scholar 

  5. R. A. Boissonnas, St. Guttmann, and P. A. Jaquenoud, Helv. Chim. Acta, 43, 1349, 1960.

    Article  CAS  Google Scholar 

  6. St. Guttmann and R. A. Boissonnas, Helv. Chim. Acta., 44, 1713, 1961.

    Article  CAS  Google Scholar 

  7. Peptides, Proceedings of the Fifth European Symposium, Pergamon Press, 261, 1963.

  8. V. Erspamer, Ann. Rev. Pharmacol., 1, 175, 1961.

    Article  CAS  Google Scholar 

  9. M. Rocha-e-Silva, Acta Physiol. latinoam., 12, 66, 1962.

    Google Scholar 

  10. I. Trautschold and G. Rüdel, Klin. Wschr., 41, 297, 1963.

    Article  CAS  Google Scholar 

  11. E. D. Nicolaides and H. A. Dewald, J. Org. Chem., 26, 3872, 1961.

    Article  CAS  Google Scholar 

  12. E. D. Nicolaides, H. A. Dewald, and D. A. McCarthy, Biophys. Res. Commun., 6, 210, 1961.

    Article  CAS  Google Scholar 

  13. J. Pless, E. Stürmer, St. Guttman, and R. A. Boissonnas, Helv. Chim. Acta., 45, 394, 1962.

    Article  CAS  Google Scholar 

  14. I. Z. Siemion, Roczniki Chem., 38, 133, 1964.

    CAS  Google Scholar 

  15. E. Schröder and R. Hempel, Exper., 20, 529, 1964.

    Google Scholar 

  16. M. Rocha-e-Silva, Ann. N. J. Acad. Sci., 104, 190, 1963.

    Article  Google Scholar 

  17. G. P. Lewis, Ann. N.J. Acad. Sci., 104, 236, 1963.

    Article  CAS  Google Scholar 

  18. G. P. Lewis, Ann. N. J. Acad. Sci., 116, 847, 1964.

    Article  CAS  Google Scholar 

  19. T. S. Paskhina, The Molecular Bases of Pathology, V. N. Orekhivicha (ed.) [in Russian], Moscow, 1965.

  20. V. N. Zykova and T. S. Paskina, DAN SSSR, 165, 1439, 1965.

    CAS  Google Scholar 

  21. W. Grassmann and E. Wünsch, Ber., 91, 462, 1958.

    CAS  Google Scholar 

  22. M. Bodanszky and V. Du. Vigneaud, J. Am. Chem. Soc., 81, 5688, 6072, 1959.

    Article  CAS  Google Scholar 

  23. D. Ben-Ishai and A. Barger, J. Org. Chem., 17, 1564, 1952.

    Article  CAS  Google Scholar 

  24. K. Heyns and G. Legler, Z. physiol. Chem., 321, 161, 1960.

    Article  CAS  Google Scholar 

  25. G. V. Lazur'evskii and Yu. N. Forostyan, ZhOKh, 29, 3498, 1959.

    CAS  Google Scholar 

  26. M. Goodman and K. Stueben, J. Am. Chem. Soc., 81, 3980, 1959.

    Article  CAS  Google Scholar 

  27. L. Zervas, M. Winitz, and G. P. Greenstein, J. Org. Chem., 22, 1515, 1957.

    Article  CAS  Google Scholar 

  28. J. V. Pierce and M. E. Webster, Biochem. Biophys. Res. Commun., 5, 353, 1961.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of the Chemistry of Natural Compounds, AS USSR, USSR

    L. A. Shchukina, G. A. Ravdel, M. P. Filatova, E. P. Semkin & S. N. Krasnova

Authors
  1. L. A. Shchukina
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  2. G. A. Ravdel
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  3. M. P. Filatova
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  4. E. P. Semkin
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  5. S. N. Krasnova
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Additional information

Khimiya Prirodnykh Soedinenii, Vol. 2, No. 2, pp. 124–130, 1966

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Shchukina, L.A., Ravdel, G.A., Filatova, M.P. et al. Synthesis of bradykinin. Chem Nat Compd 2, 97–101 (1966). https://doi.org/10.1007/BF00567544

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  • DOI: https://doi.org/10.1007/BF00567544

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