Chemistry of Natural Compounds

, Volume 12, Issue 2, pp 207–211 | Cite as

A theoretical analysis of the conformation of Ac-L-Ala-L-Pro-L-Ala-NHMe with intramolecular hydrogen bonds

  • É. P. Gromov
  • V. Z. Pletnev


1. The optimum conformations of Ac-L-Ala-L-Pro-L-Ala-NHMe with eight possible systems of intramolecular hydrogen bonds have been calculated by the method of theoretical conformational analysis.

2. The structures found serve as canonical forms for the study of the conformational states of sections of peptide-protein systems with proline residues.

3. It has been shown that the interaction of adjacent residues in the structure of the compound mentioned play the dominating role.


Gossypol Dipeptide Intramolecular Hydrogen Bond Cotton Plant Proline Residue 


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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • É. P. Gromov
  • V. Z. Pletnev

There are no affiliations available

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