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Chemistry of Natural Compounds

, Volume 13, Issue 4, pp 454–456 | Cite as

Quinazolines X. Synthesis of 6,6'-methylenebisdeoxyvasicinone and its homologs

  • Kh. M. Shakhidoyatov
  • Ch. Sh. Kadyrov
Article
  • 19 Downloads

Summary

6,6′-Methylenebisdeoxyvacisinone and its homologs have been synthesized by the reaction of methylenebisanthranilic acid with lactams (γ-butyrolactam, δ-valerolactam, ε-caprolactam, and α-chloro- and α,α-dichloro-ε-caprolactams). The condensation of anthranilic acid and its derivatives (4-nitro-, 5-bromo-, 5-iodo-, and 5-nitroanthranilic acids) with α,β-dichloro-ε-caprolactam has given seven-membered analogs of deoxyvasicinone containing two chlorine atoms in the polymethylene ring.

Keywords

Alkaloid Lactam Quinazolines Anthranilic Acid Thebaine 

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Literature cited

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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Kh. M. Shakhidoyatov
  • Ch. Sh. Kadyrov

There are no affiliations available

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