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Influence of acetylation on the iodination of thyroglobulin and the formation of thyroxine

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Summary

The results obtained show that when thyroglobulin is iodinatedin vitro the formation in it of thyroxine from the iodotyrosine residues present in it before iodination is possible. The structure of the thyroglobulin apparently plays an important role not only in the formation of thyroxine but also in the level of iodination of the protein.

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Authors
  1. T. A. Babaev
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  2. I. G. Akhmedzhanov
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  3. E. E. Gussakovskii
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  4. K. M. Ermolaev
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Additional information

Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Biological and Medicinal Chemistry, Academy of Medical Sciences of the USSR, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 485–488, July–August, 1978.

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Babaev, T.A., Akhmedzhanov, I.G., Gussakovskii, E.E. et al. Influence of acetylation on the iodination of thyroglobulin and the formation of thyroxine. Chem Nat Compd 14, 412–415 (1978). https://doi.org/10.1007/BF00565248

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  • DOI: https://doi.org/10.1007/BF00565248

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