Advertisement

Chemistry of Natural Compounds

, Volume 17, Issue 5, pp 464–469 | Cite as

Metabolites of the pathogenic fungusVerticillium dahliae. XI. Primary structure of the polypeptide moiety of the phytotoxic pigment PKZh-1

  • L. N. Ten
  • D. A. Inoyatova
  • S. Z. Mukhamedzhanov
  • O. S. Otroshchenko
Article
  • 28 Downloads

Abstract

The sequence of the 27 amino acid residues composing the polypeptide moiety of the phytotoxic metabolite PKZh-1 of the fungusV. dahliae has been determined on the basis of the structures of tryptic and chymotryptic peptides. It has been established that the linkage of the polypeptide with 2,5,7-trihydroxy-1,4-naphthoquinone (flaviolin), which is the chromophoric moiety of PKZh-1, is effected through an ester bond formed by the carboxy group of the C-terminal amino acid and one of the hydroxy groups of flaviolin.

Keywords

Amino Acid Composition Tryptic Peptide Performic Acid Guanidine Chloride Chymotryptic Peptide 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    L. N. Ten, O. S. Otroshchenko, N. N. Stepanichenko, and D. A. Inoyatova, Khim. Prirodn. Soedin., 690 (1977).Google Scholar
  2. 2.
    L. N. Ten, N. M. Mirsalikhova, and O. S. Otroshenko, Khim. Prirodn. Soedin., 59 (1979).Google Scholar
  3. 3.
    W. R. Gray, in: Methods in Enzymology, Academic Press, New York, Vol. XXV (C. H. W. Hirs and S. N. Timasheff, eds.) (1972), p. 121.Google Scholar
  4. 4.
    E. I. Vinogradova et al., Biokhimiya,38, 3 (1973).Google Scholar
  5. 5.
    T. Devenyi and J. Gergely, Amino Acids, Peptides, and Proteins, Elsevier, New York (1971).Google Scholar
  6. 6.
    B. G. Belen'kii et al., Bioorgan, Khim.,1, 396 (1975).Google Scholar
  7. 7.
    P. D. Boyer, J. Am. Chem. Soc.,76, 4331 (1954).CrossRefGoogle Scholar
  8. 8.
    J. R. Brown and B. S. Hartley, Biochem. J.,101, 214 (1966).CrossRefGoogle Scholar
  9. 9.
    A. M. Crestfield, S. Moore, and W. H. Stein, J. Biol. Chem.,238, 622 (1963).PubMedGoogle Scholar
  10. 10.
    A. S. Tsyperovich and M. V. Kolodzeiskaya, Biokhimiya,31, 564 (1966).Google Scholar
  11. 11.
    Yu. A. Ovchinnikov et al., Biokhimiya,37, 451 (1972).Google Scholar
  12. 12.
    P. D. Reshetov et al., Khim. Prirodn. Soedin., 66 (1971).Google Scholar

Copyright information

© Plenum Publishing Corporation 1982

Authors and Affiliations

  • L. N. Ten
  • D. A. Inoyatova
  • S. Z. Mukhamedzhanov
  • O. S. Otroshchenko

There are no affiliations available

Personalised recommendations