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Biosynthesis of brevicolline

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Chemistry of Natural Compounds Aims and scope

Conclusions

1. When DL-[2−14C] tryptophan, sodium [2−14C] pyrotartrate, sodium [14/C]-formate, and universally labeled L-[14C] glutamic acid were introduced through the root system intoCarex brevicollis DC, active brevicolline was obtained.

2. Tryptophan and sodium pyrotartrate are precursors of the β-carboline moiety of the brevicolline molecule, and sodium formate is a precursor of the N-methyl grouping.

3. The introduction of universally labeled L-glutamic acid does not lead to an unambiguous indication of the role of this precursor in the biosynthesis of brevicolline.

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References

  1. a) I. V. Terent'eva, in the collection: Alkaloid-Bearing Plants of Moldavia [in Russian], Kishinev, p. 21, 1960; b) P. A. Bember, I. V. Terent'eva, and G. V. Lazur'evskii, KhPS [Chemistry of Natural Compounds], 3, 249, 1967.

  2. V. M. Chernov, in the collection: Alkaloid-Bearing Plants of Moldavia [in Russian], Kishinev, p. 49, 1960; M. D. Mashkovskii, Medicinal Substances [in Russian], Moscow, p. 88, 1964.

  3. K. Mothes and H. R. Schutte, Angew. Chemie,75, 370, 1963.

    Google Scholar 

  4. E. Leete, J. Amer. Chem. Soc.,82, 6388, 1960.

    Google Scholar 

  5. E. Leete, A. Ahmad, and I. Kompis, J. Amer. Chem. Soc.,87, 4168, 1963.

    Article  Google Scholar 

  6. H. R. Schutte, Radioaktive Isotope in der organischen Chemie und Biochemie, Deutsche Verlag d. Wissenschaften, Berlin, 154, 1966.

    Google Scholar 

  7. H. R. Schutte, Radioaktive Isotope in der organischen Chemie und Biochemie, Deutsche Verlag d. Wissenschaften, Berlin, 183, 1966.

    Google Scholar 

  8. G. Hahn, L. Barwald, O. Schales, and H. Werner, Ann.520, 107, 1935; G. Hahn and F. Rumpf, Ber.,71, 2141, 1938.

    CAS  Google Scholar 

  9. E. P. Kennedy and H. A. Barker, Anal. Chem.,23, 1033, 1951.

    Article  CAS  Google Scholar 

  10. E. Leete, H. Gregory, and E. G. Gross, J. Amer. Chem. Soc.,87, 3475, 1965.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Chemistry, Slovak AS, Czechoslovakia

    I. Kompiš, E. Grossmann, I. V. Terent'eva & G. V. Lazur'evskii

  2. Institute of Chemistry, AS MoldavSSR, USSR

    I. Kompiš, E. Grossmann, I. V. Terent'eva & G. V. Lazur'evskii

Authors
  1. I. Kompiš
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  2. E. Grossmann
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  3. I. V. Terent'eva
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  4. G. V. Lazur'evskii
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Additional information

Khimiya Prirodnykh Soedinenii, Vol. 5, No. 1, pp. 39–43, 1969

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Kompiš, I., Grossmann, E., Terent'eva, I.V. et al. Biosynthesis of brevicolline. Chem Nat Compd 5, 32–35 (1969). https://doi.org/10.1007/BF00564918

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  • DOI: https://doi.org/10.1007/BF00564918

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