Summary
New derivatives of the COOH-terminal tetrapeptide of gastrin containing in place of the tryptophan residue the acyl radicals β-(1-naphthyl)acryloyl, β-(1-naphthyl)propionyl, β-(2-naphthyl)propionyl, and α-benzyloxycarbonylamino-β-(1-methylindol-3-yl)propionyl have been synthesized.
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Literature cited
I. S. Morley, F. Tracy, and R. A. Gregory, Nature,207, 1356 (1965).
Z. A. Atare, V. S. Vilka, and G. I. Chipens, Khim. Prirodn. Soedin.,5, 283 (1969).
I. M. Davey, A. Laird, and F. S. Morley, J. Chem. Soc., (C),1966, 555.
G. I. Chipens, V. S. Vilka, and Z. A. Atare, Khim. Prirodn. Soedin.,6, 117 (1970).
Additional information
Institute of Organic Synthesis, Academy of Sciences of the Latvian SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 498–503, July–August, 1971.
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Vilka, V.S., Chipens, G.I. Synthesis of analogs of a tetrapepside of gastrin with a modified tryptophan residue. Chem Nat Compd 7, 472–475 (1971). https://doi.org/10.1007/BF00564741
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DOI: https://doi.org/10.1007/BF00564741