Advertisement

Chemistry of Natural Compounds

, Volume 7, Issue 4, pp 451–455 | Cite as

Synthesis of protected peptides representing fragments (14–22) and (11–17) of yeast cytochrome c

  • N. L. Alarkon
  • S. D. L'vova
  • R. P. Evstigneeva
Article
  • 18 Downloads

Summary

The synthesis of a nonapeptide, the benzyl ester of Nα-benzyloxycarbonyl-S-benzyl-L-cysteinyl-γ-benzyl-L-glutamyl-L-leucyl-S-benzyl-L-cysteinyl-Nim-benzyl-L-histidyl-L-threonyl-L-valyl-γ-benzyl-L-glutamyl-Nε-tosyl-L-lysine (XIII), and a heptapeptide, the benzyl ester of Nα-benzyloxycarbonyl-Nε-tosyl-L-lysyl-L-threonyl-nitro-L-arginyl-S3-benzyl-L-cysteinyl-γ-methyl-L-glutamyl-L-leucyl-S-benzyl-L-cysteine (VII), corresponding to the sequences 14–22 and 11–17 of yeast cytochrome c, has been effected.

Keywords

Caustic Soda Benzyl Ester Mixed Anhydride Caustic Potash OCOC 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    S. D. L'vova, R. P. Evstigneeva, S. A. Mel'nikova, I. N. Ryabova, and N. A. Preobrazhenskii, Zh. Obshch. Khim.,40, 242 (1970).Google Scholar
  2. 2.
    S. D. L'vova, I. N. Sologubovskaya, and R. P. Evstigneeva, Zh. Obshch. Khim.,41, 216 (1971).Google Scholar
  3. 3.
    H. Zahn and M. Schüssler, Ann. Chem.,641, 176 (1961).CrossRefGoogle Scholar
  4. 4.
    K. Hofmann, W. D. Peckman, and A. Rheiner, J. Amer. Chem. Soc.,78, 238 (1956).CrossRefGoogle Scholar
  5. 5.
    M. Manning and V. du Vigneaud, J. Amer. Chem. Soc.,92, 6842 (1969).Google Scholar
  6. 6.
    M. Bodansky, J. Meienhofer, and V. du Vigneaud, J. Amer. Chem. Soc.,82, 3195 (1960).CrossRefGoogle Scholar
  7. 7.
    G. Steinman, Exper.,23, 177 (1967).Google Scholar
  8. 8.
    C. B. Anfinsen, D. Ontjes, M. Ohno, L. Corley, and A. Eastlake, Proc. Natl. Acad. Sci. U. S.,58, 1806 (1967).CrossRefGoogle Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1973

Authors and Affiliations

  • N. L. Alarkon
  • S. D. L'vova
  • R. P. Evstigneeva

There are no affiliations available

Personalised recommendations