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Synthesis and some physicochemical properties of antamanide, retroantamanide, and perhydroantamanide

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The synthesis of antamanide, retroantamanide, and perhydroantamanide has been effected. It has been shown that the inversion of the direction of acylation — the equilibrium interchange of the valine and alanine residues (retroantamanide) — lowers the stability of the complexes with sodium and potassium in ethanolic solutions, while the replacement of the phenyl groups by cyclohexyl groups has practically no effect on complex formation.

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M. M. Shemyakin Institute of the Chemistry of Natural Compounds, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 469–474, July–August, 1971.

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Ovchinnikov, Y.A., Ivanov, V.T., Miroshnikov, A.I. et al. Synthesis and some physicochemical properties of antamanide, retroantamanide, and perhydroantamanide. Chem Nat Compd 7, 445–450 (1971). https://doi.org/10.1007/BF00564736

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  • DOI: https://doi.org/10.1007/BF00564736

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