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Synthesis of [1-(ethyl ester of carbonylglycine), 5-valine]angiotensin II and [1-(carbonylglycinamide), 5-valine]angiotensin II

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Summary

[1-Carbonylglycinamide, 5-valinelangiotensin II — a biologically highly active hybrid of angiotensin and vasopressin in which the NH2-terminal amino acid of angiotensin has been replaced by the COOH-terminal amino acid of vasopressin — has been synthesized.

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Authors and Affiliations

  1. Academy of Sciences of the Latvian SSR, Institute of Organic Synthesis, Russia

    R. É. Vegner, G. I. Chipens & Z. P. Auna

Authors
  1. R. É. Vegner
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  2. G. I. Chipens
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  3. Z. P. Auna
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Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 92–95, January–February, 1972.

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Vegner, R.É., Chipens, G.I. & Auna, Z.P. Synthesis of [1-(ethyl ester of carbonylglycine), 5-valine]angiotensin II and [1-(carbonylglycinamide), 5-valine]angiotensin II. Chem Nat Compd 8, 86–88 (1972). https://doi.org/10.1007/BF00564447

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  • DOI: https://doi.org/10.1007/BF00564447

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