Chemistry of Natural Compounds

, Volume 2, Issue 6, pp 307–310 | Cite as

Furocoumarins ofCnidium dubium

  • N. F. Komissarenko
  • V. T. Chernobai


1. Paper chromatography has shown that the fruit ofC. dubium contains not less than eight substances of coumarinic nature; six of these (A, B, C, D, E, and H) have been isolated in the crystalline state.

2. Substances B, D, and E are identical with isoimperatorin, imperatorin, and oxypeucedanin, respectively. Some properties of substance H have been determined. Prangenin [F] has been detected in the fruit ofC. dubium by paper chromatography.

3. The structure of two new compounds has been established: substance A (cnidicin) (I) is 5, 8-di-(γ, γ-dimethylallyloxy) psoralen, and substance C (cnidilin) (II) is 5-(γ, γ-dimethylallyloxy)-8-methoxypsoralen.


Coumarin Psoralen Sulfanilic Acid Imperatorin Anhydrous Potassium Carbonate 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    V. T. Chernobai and D. G. Kolesnikov, DAN SSSR,133, no. 1, 233, 1960.Google Scholar
  2. 2.
    I. G. Zoz, N. F. Komissarenko, V. T. Chernobai, and D. G. Kolesnikov, DAN SSSR,162, no. 6, 1423, 1965.Google Scholar
  3. 3.
    N. F. Komissarenko and D. G. Kolesnikov, Abstracts of Papers and Communications, IXth Mendeleev Congress [in Russian], no. 4, 271, 1965.Google Scholar
  4. 4.
    E. Späth and H. Holzen. Ber.,66, 1137, 1933.Google Scholar
  5. 5.
    T. H. Simpson and J. L. Beton. J. Chem. Soc., 4065, 1954.Google Scholar
  6. 6.
    D. G. Kolesnikov, N. F. Komissarenko, and V. T. Chernobai, Med. prom. SSSR, no. 6, 32, 1961.Google Scholar
  7. 7.
    N. F. Komissarenko, V. T. Chermobai, and D. G. Kolesnikov, Terpenoids and Coumarins [in Russian], 58, 1965.Google Scholar
  8. 8.
    G. N. Nikonov and D. I. Baranauskaite, KhPS, [Chemistry of Natural Compounds], 139, 1965.Google Scholar
  9. 9.
    Yu. A. Dranitsina, G. V. Pigulevskii, and T. V. Bukreeva, ZhPKh,38, no. 11, 2570, 1965.Google Scholar
  10. 10.
    T. Beyrich, Arch. Pharmaz.,298, no. 10, 672, 1965.CrossRefGoogle Scholar

Copyright information

© The Faraday Press, Inc. 1968

Authors and Affiliations

  • N. F. Komissarenko
    • 1
  • V. T. Chernobai
    • 1
  1. 1.Khar'kov Chemical and Pharmaceutical Scientific Research InstituteUSSR

Personalised recommendations