Chemistry of Natural Compounds

, Volume 10, Issue 3, pp 291–296 | Cite as

Synthesis of new valinomycin analogs. II

  • E. I. Vinogradova
  • L. A. Fonina
  • I. D. Ryabova
  • V. T. Ivanov


1. The synthesis of eight cycloocta- and cyclododecapepsipeptide analogs of valinomycin containing different numbers of ester, amide, and N-methyl amide bonds has been effected.

2. The stability constants of the complexes of these analogs with potassium ions in ethanolic solution has been determined.

3. The antimicrobial activity of the compounds obtained has been studied.


Stability Constant Magnesium Sulfate Valinomycin Palladium Black Dibutyl Ether 


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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • E. I. Vinogradova
  • L. A. Fonina
  • I. D. Ryabova
  • V. T. Ivanov

There are no affiliations available

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