Chemistry of Natural Compounds

, Volume 8, Issue 3, pp 286–289 | Cite as

Granilin — A new lactone from Inula grandis

  • L. P. Nikonova
  • G. K. Nikonov


From the epigeal part ofInula grandis Schrenk., collected in the rosette-incipient stem formation period, a new sesquiterpene lactone has been isolated with the formula C15H20O4, mp 197–198°C, [α] D 25 +147.9° (acetone), and we have called it granilin. On the basis of the NMR spectra of the initial substance and the products of its hydrogenation and acetylation, it has been established that granilin has the most probable structure of 1,3-dihydroxyeudesma-4(14), 11(13)-dien-7,8-olide.


Lactone Sesquiterpene Lactone Paramagnetic Shift Alantolactone Iodic Acid 


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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • L. P. Nikonova
  • G. K. Nikonov

There are no affiliations available

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