Granilin — A new lactone from Inula grandis
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From the epigeal part ofInula grandis Schrenk., collected in the rosette-incipient stem formation period, a new sesquiterpene lactone has been isolated with the formula C15H20O4, mp 197–198°C, [α] D 25 +147.9° (acetone), and we have called it granilin. On the basis of the NMR spectra of the initial substance and the products of its hydrogenation and acetylation, it has been established that granilin has the most probable structure of 1,3-dihydroxyeudesma-4(14), 11(13)-dien-7,8-olide.
KeywordsLactone Sesquiterpene Lactone Paramagnetic Shift Alantolactone Iodic Acid
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- 1.L. P. Nikonov and G. K. Nikonov, Khim. Prirodn. Soedin., 133 (1970).Google Scholar
- 2.A. Weissberger, Determination of the Structure of Organic Compounds by Physical and Chemical Methods [Russian translation], Moscow (1967), p. 92.Google Scholar
- 3.L. Bellamy, Infra-Red Spectra of Complex Molecules, 2nd ed., Methuen (1958).Google Scholar
- 9.K. S. Rybalko, A. I. Ban'kovskii, and V. I. Sheichenko, in: Medicinal Plants, Vol. 15 (Chemistry) [in Russian], Moscow (1969), p. 290.Google Scholar