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Synthesis of regular polypeptides including lysine, proline, and alanine residues

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Chemistry of Natural Compounds Aims and scope

Conclusions

Polypeptides of the following sequences have been obtained: -Lys-Pro-,-Lys2-Pro-, -Lys3-Pro-,-Lys-Pro2-, and -Lys-Ala-, with molecular weights of from 1000 to 14,000. It has been established that the use of pentachlorophenyl esters for polymerization in place of 2,4,5-trichlorophenyl esters leads to a considerable increase in the molecular weights of the polypeptides.

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Literature cited

  1. D. M. P. Phillips (Editor), Histones and Nucleohistones, Plenum (1971).

  2. K. T. Poroshin, V. K. Burichenko, L. I. Mar'yash, and V. S. Shibnev, Izv. Akad. Nauk SSSR, Ser. Khim., 1276 (1971).

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Authors
  1. L. I. Mar'yash
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  2. V. A. Shibnev
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Additional information

Institute of Chemistry, Academy of Sciences of Tadzhik SSR. Institute of Molecular Biology, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 210–213, March–April, 1974.

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Mar'yash, L.I., Shibnev, V.A. Synthesis of regular polypeptides including lysine, proline, and alanine residues. Chem Nat Compd 10, 216–218 (1974). https://doi.org/10.1007/BF00563617

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  • DOI: https://doi.org/10.1007/BF00563617

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