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The structure of karakoline

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Summary

We have isolated from the tubers ofAconitum karakolicum collected in the Kirghiz SSR, Kungei Alatau range, songorine, napelline, a base with mp 159–160°C, and the new alkaloids karakoline and a base with mp 222–224°C.

The results of a study of the chemical reactions and spectral characteristics of karakoline have shown that it consists of a lycoctonine skeleton with N-ethyl and C4-methyl groups, hydroxyls at C1, C8, and C10 and a methoxy group at C15.

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Literature cited

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Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 199–205, March–April, 1973.

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Sultankhodzhaev, M.N., Yunusov, M.S. & Yunusov, S.Y. The structure of karakoline. Chem Nat Compd 9, 194–198 (1973). https://doi.org/10.1007/BF00563343

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