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Kinetics of the formylation of thiophene derivatives with N,N-dimethylformamide

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The kinetics of the formylation of five thiophene derivatives in the presence of phosphorus oxychloride and the formylation of thiophene in the presence of thionyl chloride were investigated. The effect of the condensing agent on the reaction rate is shown, and the rate constants and the activation parameters are calculated. The isokinetic dependence and the Hammett dependence of the reactivities on the structure were established for this reaction series. The effect of the solvent on the formylation was studied.

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Authors and Affiliations

  1. All-Union Scientific-Research and Design Institute of Monomers, 300026, Tula

    G. N. Freidlin, N. A. Kuraeva & K. A. Solop

Authors
  1. G. N. Freidlin
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  2. N. A. Kuraeva
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  3. K. A. Solop
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 315–319, March, 1980.

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Freidlin, G.N., Kuraeva, N.A. & Solop, K.A. Kinetics of the formylation of thiophene derivatives with N,N-dimethylformamide. Chem Heterocycl Compd 16, 230–233 (1980). https://doi.org/10.1007/BF00553882

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  • DOI: https://doi.org/10.1007/BF00553882

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