Abstract
In the reaction of β-(5-bromouracil-1-yl)-α-analine with primary or secondary amines an imidazo[1,2-c]pyrimidine is formed.
Similar content being viewed by others
Literature cited
M. Yu. Likak, R. A. Paegle, M. G. Plata, and Yu. P. Shvachkin, Khim. Geterotsikl. Soedin., No. 4, 530 (1971).
M. Roberts and D. W. J. Visser, J. Am. Chem. Soc.,74, 668 (1952).
D. E. O'Brien, C. W. Noell, R. K. Robins, and C. C. Cheng, J. Med. Chem. Soc.,9, 121 (1966).
A. Benitez, L. O. Ross, L. Goodman, and B. R. Baker, J. Am. Chem. Soc.,82, 4585 (1960).
H. Bredereck, G. Kupsch, and H. Wieland, Chem. Ber.,92, 583 (1959).
A. P. Phillips, J. Am. Chem. Soc.,72, 1061 (1951).
T. Ueda, Chem. Pharm. Bull.,8, 455 (1960).
J. M. Rice, G. O. Dudek, and M. Barber, J, Am. Chem. Soc.,87, 4569 (1965).
T. K. Bradshaw and D. W. Hutchinson, Chem. Soc. Rev.,6, 43 (1977).
D. Lipkin, C. Cori, and M. Sano, Tetrahedron Lett., 5993 (1968).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 538–540, April, 1980.
Rights and permissions
About this article
Cite this article
Paégle, R.A., Lulle, I.Z., Krishane, V.É. et al. Transformation of β-(5-bromouracil-1-yl)-α-alanine into an imidazo[1,2-c]pyrimidine. Chem Heterocycl Compd 16, 418–420 (1980). https://doi.org/10.1007/BF00552785
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00552785