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New examples of the vinylation of NH-heterocycles with acetylene at atmospheric pressure in the KOH-DMSO system

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Vinylation of 2-hetarylpyrroles, 4,5-dihydrobenzo[g]indole, and 1,2,3,4-tetrahydro-γ-carbinols at atmospheric pressure in the superbasic system KOH-DMSO at 100–120 ° C has given the corresponding N-vinyl derivatives in yields of 92–99%.

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Literature cited

  1. B. A. Trofimov and A. I. Mikhaleva, N-Vinylpyrroles [in Russian], Nauka, Novosibirsk (1984), p. 260.

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  2. G. G. Skvortsova, E. S. Domnina, N. P. Glazkova, and L. P. Makhno, Proc. 3rd All-Union Conf. on Acetylene Chemistry [in Russian], Nauka (1972), p. 115.

  3. M. V. Sigalov, Diss. Cand. Chem. Sci., [in Russian], Irkutsk (1979), p. 116.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 481–485, April, 1986.

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Trofimov, B.A., Nesterenko, R.N., Mikhaleva, A.I. et al. New examples of the vinylation of NH-heterocycles with acetylene at atmospheric pressure in the KOH-DMSO system. Chem Heterocycl Compd 22, 393–396 (1986). https://doi.org/10.1007/BF00542777

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  • DOI: https://doi.org/10.1007/BF00542777

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