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Research in the imidazole series. 93. Synthesis of derivatives of benzimidazolyl-1-acetic acid

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A simple method has been developed for obtaining esters of benzimidazolyl-1-acetic acid and its 2-alkyl (or aralkyl) derivatives, by reaction of benzimidazoles with esters of chloroacetic or bromoacetic acid in DMF in the presence of anhydrous potassium carbonate. The method of synthesis of amides of these acids has been simplified.

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References

  1. P. M. Kochergin, A. A. Druzhinina, R. M. Palei, and O. N. Minailova, Khim. Geterotsikl. Soedin., No. 2, 225 (1977).

    Google Scholar 

  2. D. Jerkel, M. Kracht, and K. Krucker, Justus Liebigs Ann. Chem., 590, 232 (1954).

    Google Scholar 

  3. S. Takahashi and H. Kano, J. Org. Chem., 30, 1118 (1965).

    Google Scholar 

  4. F. Caoace, R. Guiliano, and J. Haq, Atti Accad. Naz. Lincei, Rend., Classe Sci. Fiz. Mat. Nat., 22, 510 (1957) [Chem. Abstr., 52, 5725a (1958)].

    Google Scholar 

  5. P. M. Kochergin, R. M. Palei, and S. A. Chernyak, in: Summaries of Papers from 2nd Moscow Conference on Organic Chemistry and Technology [in Russian], Moscow (1979), p. 58.

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Authors and Affiliations

  1. All-Russian Scientific-Research Chemical-Pharmaceutical Institute, Center for the Chemistry of Pharmaceutical Substances, 119815, Moscow

    P. M. Kochergin, R. M. Palei & S. A. Chernyak

Authors
  1. P. M. Kochergin
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  2. R. M. Palei
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  3. S. A. Chernyak
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Additional information

For Communication 92, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, Vol. 29, No. 5, pp. 656–658, May, 1993.

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Kochergin, P.M., Palei, R.M. & Chernyak, S.A. Research in the imidazole series. 93. Synthesis of derivatives of benzimidazolyl-1-acetic acid. Chem Heterocycl Compd 29, 560–562 (1993). https://doi.org/10.1007/BF00534469

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  • DOI: https://doi.org/10.1007/BF00534469

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