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Chemistry of Heterocyclic Compounds

, Volume 29, Issue 8, pp 966–971 | Cite as

Investigation of heterocycles containing nitrogen or sulfur. 48. Derivatives of 1-morpholinooxalyl-1,2-dihydrothiazolo-[5,4-b]pyridine, their structure, and reactions

  • N. P. Solov'eva
  • O. S. Anisimova
  • E. M. Peresleni
  • K. F. Turchin
  • Yu. N. Sheinker
  • L. G. Levkovskaya
  • L. A. Serochkina
  • T. S. Safonova
Article
  • 35 Downloads

Abstract

The structures of the products of reactions of 1-N-morpholinooxahi-1,2-dihydrothiazolo-[5,4-b]pyridine have been studied by IR, NMR, UV, and mass spectroscopy. Geometric (cis-anti) and rotational (about the CO-N amide bond) isomers of 1-N-morpholinooxalyl-2-propionyi-5-chloro-1,2-dihydrothiazolo-[5,4-b]pyridine oxime have been observed and studied. Treatment of 1-N-morpholinooxalyl-2-propionyl-5-chloro-1,2-dihydrothiazolo[5,4-b]pyridine with ethanolic alkali gave 2-propionyl-5-chlorothiazolo-[5,4-b]pyridine, while treatment with concentrated H2SO4 gave 1,2-dioxo-ethylidene-7-chloroxazolidino[3,2-f]pyrido[2,3-b]1,4-thiazine.

Keywords

Nitrogen Sulfur Spectroscopy Mass Spectroscopy Organic Chemistry 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • N. P. Solov'eva
    • 1
  • O. S. Anisimova
    • 1
  • E. M. Peresleni
    • 1
  • K. F. Turchin
    • 1
  • Yu. N. Sheinker
    • 1
  • L. G. Levkovskaya
    • 1
  • L. A. Serochkina
    • 1
  • T. S. Safonova
    • 1
  1. 1.Institute of Medicinal ChemistryVNIKhFIMoscow

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