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Chemistry of Heterocyclic Compounds

, Volume 29, Issue 8, pp 959–965 | Cite as

Investigation of heterocycles containing nitrogen or sulfur. 47. Reactions of 1,2-dioxo-3a-alkyl-4,7-dichloroxazolidino [3,2-f]pyrido[2,3-b]-1,4-thiazines with saturated cyclic amines. synthesis and structure of derivatives of 1,2-dihydrothiazolo[5,4-b]pyridine

  • N. P. Solov'eva
  • O. S. Anisimova
  • E. M. Peresleni
  • K. F. Turchin
  • Yu. N. Sheinker
  • L. G. Levkovskaya
  • L. A. Serochkina
  • T. S. Safonova
Article
  • 33 Downloads

Abstract

It has been established spectroscopically that 1-N-oxalamides of 2-acyl-5-chloro-1,2-dihydrothiazolo[5,4-b] pyridine are formed in the reaction of 4,7-dichloroxazolidino[3,2-f]pyrido[2,3-b]-1,4-thiazines with morpholine, piperidine and pyrrolidine. The products are a mixture of amide conformers in solution. The reaction intermediate 2-(1-chloro-2-oxobutylthio)-3-pyrrolidinooxamoyl-6-chloropyridine has been isolated and characterized. A proposed reaction scheme is presented.

Keywords

Nitrogen Sulfur Organic Chemistry Amide Pyridine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • N. P. Solov'eva
    • 1
  • O. S. Anisimova
    • 1
  • E. M. Peresleni
    • 1
  • K. F. Turchin
    • 1
  • Yu. N. Sheinker
    • 1
  • L. G. Levkovskaya
    • 1
  • L. A. Serochkina
    • 1
  • T. S. Safonova
    • 1
  1. 1.Institute of Medicinal ChemistryVNIKhFIMoscow

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