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Chemistry of Heterocyclic Compounds

, Volume 29, Issue 8, pp 955–958 | Cite as

Synthesis of heterocycles using products of the addition of polyhaloalkanes to unsaturated systems. 5. Synthesis of substituted thiazoles

  • A. A. Dudinov
  • L. I. Belen'kii
  • M. M. Krayushkin
Article
  • 44 Downloads

Abstract

First syntheses are reported for 2-aminothiazoles, 2-chlorothiazoles, and 2-thiazolones with a 2,2,-trichloroethyl group at C(5) using the products of the homolytic addition of CCl4 and trichloroacetonitrile to methyl vinyl ketone. Further transformation of this substituent may be carried out for the preparation of compounds with possible biological activity.

Keywords

Methyl Organic Chemistry Biological Activity Ketone Vinyl 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • A. A. Dudinov
    • 1
  • L. I. Belen'kii
    • 1
  • M. M. Krayushkin
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryRussian Academy of SciencesMoscow

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